Endocrine Abstracts

ObjectiveThere is limited clinical data available on bilateral adrenal masses (BAM). Here we present a case with BAC and adrenal insufficiency. The patient’s lesions disappeared after steroids, re-grew in the follow-up, allowing a biopsy.CaseA 60-year-old male patient presented with abdominal pain, nausea, and weakness to another hospital. Hyponatremia and hyperkalemia accompanied by hypotension were det...

IntroductionHypercholesterolemia may develop due to primary and secondary causes. Diabetes mellitus, hypothyroidism, nephrotic syndrome and liver diseases are among the most common causes of secondary hyperlipidemia. Here, we will present a case with severe hyperlipidemia due to primary sclerosing cholangitis(PSC).CaseA 36-year-old male patient was admitted to our outpatient clinic due to severe hypercholeste...

BackgroundPheochromocytomas are rare tumors originating from chromaffin cells and characterized by excessive catecholamine synthesis. They are usually benign lesions. Hypertension(HT), tachycardia, sweating and headache are frequently observed. We aimed to present a high malignancy suspected pheochromocytoma case diagnosed in a young age female.Case presentationA 20-year-old female patient was admitted to the...

BackgroundPituitary xanthogranulomas are extremely rare tumors of the sellar region. A cystic mass lesion was found in the pituitary MRI of our patient diagnosed with central diabetes insipidus (DI). We aimed to present a case who was operated for a pituitary mass and diagnosed with sellar xanthogranuloma.Case presentation37-year-old female patient was applied to our outpatient clinic with complaints of polyd...

IntroductionGlucagonoma is an extremely rare type of functional pancreatic neuroendocrine tumor that is characterized by distinctive clinical manifestations such as diabetes mellitus, weight loss, deep vein thrombosis, and necrolytic migratory erythema which represents the hallmark clinical sign of glucagonoma syndrome. Here, we report the case of a 53-year-old male patient who presented with high amilase and lipase levels. In further investigation a pan...

PurposePoorly differentiated thyroid carcinoma (PDTC); is a rare type of thyroid cancer with a high risk of recurrence, metastasis, and death. Pleural effusion due to thyroid cancer has seldom been reported. In this report, we present a case with PDTC related malignant pleural effusion.CaseA 66-year-old male patient presented with neck swelling and shortness of breath. At another center, thyroid ultrasonograp...

IntroductionThyroid cancer is the most common endocrine malignancy and its overall incidence has increased significantly in the last 30 years. Cancer in adolescents and young adults (AYA) is defined by the National Cancer Institute as diagnoses occurring among those aged 15 to 39 years. Thyroid cancer is the second most common cancer in the AYA population. In this study, we aimed to compare clinical, ultrasonographical, cytological and histopathological ...

IntroductionExtramedullary plasmacytoma (EMP) is a plasma cell neoplasm of extraosseous tissues. Less than 5% of all plasma cell neoplasms develop extramedullary. EMP is most common in the upper respiratory tract and oral cavity. The thyroid gland is one of the extremely rare regions. It is more common in men and the average age at diagnosis is 55. Primary thyroid plasmacytoma is one of the rare thyroid neoplasms. It often manifests as a rapidly growing ...

IntroductionIt is recommended to determine levothyroxine (LT4) dose individually in patients with hypothyroidism. However, higher doses of LT4 therapy are required to achieve target TSH levels in significant number of patients. Oral LT4 absorption occurs in the small intestine, especially in the jejunum and proximal ileum, while a small amount is absorbed in duodenum. Causes of LT4 malabsorption include helicobacter pylori infection, chronic atrophic gas...

The co-occurrence of congenital adrenal hyperplasia and type 1 diabetes mellitus (T1DM) is a rare phenomenon in existing literature. The primary cause of congenital adrenal hyperplasia (CAH) is often 21-hydroxylase deficiency (21OHD), a condition associated with the CYP21A2 gene located on chromosome 6p21.3 within the major human leukocyte antigen (HLA) histocompatibility locus. Various gene polymorphisms, particularly in HLA-DQalpha, DQbeta, and DR genes on chromosome 6p21.32...